EKSPERIMENTAL DIABET MODELIDA OSHQOZON OSTI BEZI LANGERGANS OROLCHALARINI AJRATIB OLISH VA ANTIOKSIDANT PREPARATNING TA’SIRI
https://doi.org/10.5281/zenodo.20502899
Keywords:
Oshqazon osti bezi, in situ, β-hujayra, qandli diabet, kversetin, maxsar o‘simligi ekstrakti, oqsil miqdoriAbstract
Eksperimental diabet modelida “Maxsar” o‘simligi ekstrakti oshqozon osti bezi Langerhans orolchalarini oksidativ stressdan himoya qilib, glyukozani pasaytirish va insulin sekretsiyasini yaxshilash natijasini o‘rganib chiqildi. Davolash oksidativ stress markerlarini yaxshiladi va beta-hujayra zichligini qisman tiklashi o‘rganildi. Natijalar ekstraktning antigiperglyemik va antioksidant ta’sirlarini ko‘rsatdi, ammo molekulyar mexanizmlar va xavfsizligini aniqlash uchun qo‘shimcha tadqiqotlar zarur.
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References
Wakabayashi T. et al. Immunomodulating activities of polysaccharide fractions from dried safflower petals //Cytotechnology. – 1997. – Т. 25. – №. 1. – С. 205-211.
Mohammed G. F. et al. Effect of safflower (Carthamus tinctorius) on the biochemical profile of blood serum and insulin levels in alloxan-induced diabetic rats //Regulatory Mechanisms in Biosystems. – 2025. – Т. 16. – №. 1. – С. e25023-e25023.
Graham K. L. et al. Isolation and culture of the islets of Langerhans from mouse pancreas. Bio-protocol 2015; 6 (12): e1840 [Электронный ресурс].
Samaddar S., Jha D. K., Koneri R. Optimization of pancreatic islet isolation from rat and evaluation of islet protective potential of a saponin isolated from fruits of Momordica dioica //Journal of Applied Pharmaceutical Science. – 2020. – Т. 10. – №. 7. – С. 089-099.
Mustafaqulov M. et al. Qandli diabet experimental modelida maxsar (carthamus tinctorius l) ekstraktining gipoglykemik ta’sirini o ‘rganish //Scientific practical conference. – 2025. – Т. 1. – №. 1. – С. 145-147.
Umarjonovna I. S. et al. Mеtabolik sindrom va qandli diabet asosiy va nazorat guruhi na’munalarida adrβ2 gеni rs1042714 polimorfizmining allеl va gеnotipik variantlarini tarqalishi //american journal of education and learning. – 2024. – Т. 2. – №. 4. – С. 674-681.
Makhramovna M. M., Abduvaliyevich M. M. The effect of polyphenol compounds on ca2+-induced mitochondrial potorage (mptp) in toxic hepatitis //american journal of applied science and technology Учредители: The USA Journals. – 2024. – Т. 4. – №. 10. – С. 126-135.
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