PROBIOTIK MIKROORGANIZMLAR VA QISQA ZANJIRLI YOG‘ KISLOTALARINING DIABETDA TA’SIRI BO‘YICHA QIYOSIY TAHLILAR
Keywords:
Qandli diabetning 2-tipi, probiotik bakteriyalar, lactobacillus, bifidobacterium, firmicutes, bacteridetes, qisqa zanjirli yog‘ kislotalari, butirat kislota, glikozillangan gemoglobinAbstract
So‘nggi yillarda ichak mikrobiotasining metabolik kasalliklar, shu jumladan qandli diabet patogenezidagi o‘rni tobora ko‘proq ilmiy qiziqish uyg‘otmoqda. Ichak mikroflorasining tarkibiy va funksional o‘zgarishlari energiya almashinuvi, glyukoza gomeostazi, shuningdek immun javob mexanizmlariga samarali ta’sir ko‘rsatishi hamda qandli diabet kasalligining kelib chiqish sabablari, qisqa zanjirli yog‘ kislotalari, oziq-ovqat ratsioni va mikrobiota o‘zaro ta’siri, firmicutes-bacteridetes, probiotik bakteriyalar lactobacillus hamda bifidobacteriyalarning diabet kasalligiga ta’siri, samaradorligini aniqlash bo‘yicha mavjud bo‘lgan ilmiy ma’lumotlar tizimli tahlil qilinadi.
Downloads
References
McMurdie PJ, Stoeva MK, Justice N, Nemchek M, Sieber CMK, Tyagi S, Gines J. Skennerton CT, Souza M, Kolterman O, Eid J. Increased circulating butyrate and ursodeoxycholate during probiotic intervention in humans with type 2 diabetes. BMC Microbiol. 2022 Jan 8;22(1):19. doi: 10.1186/s12866-021-02415-8. PMID34996347;PMCID:MC8742391.https://pubmed.ncbi.nlm.nih.gov/34996347/
Kassaian N, Feizi A, Aminorroaya A, Jafari P, Ebrahimi MT, Amini M. Clinical application of probiotics in type 2 diabetes mellitus: A randomized, double-blind, placebo-controlled study. Clin Nutr. 2017;36(2):516–523. doi: 10.1016/j.clnu.2015.11.018. PMID: 26706047. https://pubmed.ncbi.nlm.nih.gov/26706047/
Sato, J., Kanazawa, A., Azuma, K. et al. Probiotic reduces bacterial translocation in type 2 diabetes mellitus: A randomised controlled study. Sci Rep 7, 12115 (2017). https://doi.org/10.1038/s41598-017-12535-9
O’Connor S, Chouinard-Castonguay S, Gagnon C, Rudkowska I. Improvements to postprandial glucose control in subjects with type 2 diabetes: a randomized placebo-controlled probiotic trial. Nutrients. 2020;12(7):2111. doi: 10.3390/nu12072111. PMID: 32679759; PMCID: PMC7368581
Downloads
Published
Conference Proceedings Volume
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
