1-TUR QANDLI DIABET DIAGNOSTIKASIDA IMMUNOFERMENT TAHLIL TIZIMLARINING BIOTEXNOLOGIK ASOSLARI
https://doi.org/10.5281/zenodo.20484163
Keywords:
1-tur qandli diabet, ICA, Anti-GAD, autoimmun diagnostika, biomarkerlar, seropozitivlik, preklinik bosqich, skriningAbstract
Tadqiqotning ushbu qismida oilaviy moyillikka ega bo‘lgan bemorlarda qandli diabetning (QD) immunogenetik tabiatini baholash maqsadida o‘ziga xos immunologik markerlar tahlil qilindi. Asosiy diagnostik mezon sifatida me’da osti bezi orolli hujayralarining sitoрlazmatik antigenlariga qarshi yo‘naltirilgan autoantitanalar (ICA tanlab olindi. Ushbu markerlar me’da osti bezidagi endokrinositlarning destruktiv jarayonlarini aks ettiruvchi eng erta va informativ ko‘rsatkichlardan biri bo‘lib, klinik belgilarsiz kechadigan destruksiya fazasini monitoring qilish imkonini beradi.
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